Discover the AVEA Ingredients Glossary

NMN (Nicotinamide Mononucleotide) is a vital molecule your body uses to produce NAD+, a coenzyme essential for cellular energy and function. As we age, NAD+ levels naturally decline, leading to fatigue and slower repair processes. Longevir™ NMN is designed to boost these levels efficiently, helping to rejuvenate cells from within, enhance physical endurance, and support optimal metabolic health for a longer, healthier life.

Betaine acts as a methyl donor, a critical process for DNA regulation and protein function. It is essential for converting homocysteine—a compound that can be harmful in high amounts—back into methionine, thereby supporting heart and blood vessel health. Additionally, Betaine supports liver detoxification processes and helps maintain proper hydration balance within cells.

Apigenin is a natural flavonoid responsible for the calming effects of chamomile. In the context of longevity, it plays a strategic role by inhibiting CD38, an enzyme that breaks down NAD+ as we age. By slowing this breakdown, Apigenin helps maintain higher NAD+ levels for longer periods. It also possesses antioxidant and soothing properties, supporting neuronal health and relaxation.

Found in blueberries, Pterostilbene is chemically similar to Resveratrol but is more bioavailable, meaning your body absorbs and utilizes it more easily. It works to support healthy inflammation levels, promote cognitive health, and protect cells against age-related damage. Its superior stability allows it to stay in the system longer, providing sustained support for your longevity pathways.

We use Veri-te™ Trans-Resveratrol, a high-purity form of this famous polyphenol. Resveratrol is known to activate Sirtuins, the “longevity genes” associated with DNA repair and metabolic regulation. It mimics the beneficial effects of calorie restriction and exercise on the body. As a strong antioxidant, it also combats oxidative stress, supporting heart health and healthy brain function.

Nicotinamide is a water-soluble form of Vitamin B3 that is gentle on the body. It plays a key role in the synthesis of NAD+, the molecule responsible for converting nutrients into energy. Beyond energy metabolism, Nicotinamide supports the health of the nervous system and skin, helping to maintain a strong barrier and improve texture. It is included to support the overall NAD+ salvage pathway.

Coenzyme Q10 is found in every cell of the body and is crucial for producing energy in the mitochondria. We use Kaneka Ubiquinol®, the active and most absorbable form of CoQ10. It acts as a potent antioxidant, protecting cells from oxidative stress while supporting cardiovascular health and sustaining vitality. It works synergistically with other longevity ingredients to maximize cellular efficiency.

Ergothioneine is an amino acid found in mushrooms that has a specific transporter in the human body, indicating its biological importance. It concentrates in tissues subjected to high oxidative stress, like the liver and eyes. It is exceptionally stable and protects cellular DNA and mitochondria from damage, supporting long-term cellular integrity.

Spermidine is a polyamine that mimics the benefits of fasting. It activates autophagy, a critical recycling process where cells clean out damaged components and toxic proteins. This cellular “spring cleaning” is essential for cellular renewal, longevity, and maintaining healthy organ function as we age.

Pyrroloquinoline Quinone (PQQ) is unique because it promotes mitochondrial biogenesis—the creation of new power plants within your cells. While CoQ10 improves the function of existing mitochondria, PQQ helps build fresh ones. It is also a neuroprotective agent, supporting memory, attention, and protecting brain cells from oxidative damage.

Selenium is a critical cofactor for glutathione peroxidase, one of the body’s most important internal antioxidant enzymes. By supporting this enzyme system, Selenium helps protect cells from DNA damage and oxidative stress. It is also essential for proper thyroid function, metabolism, and maintaining a healthy immune system response.

Quercefit® uses a phytosome technology to increase Quercetin absorption by up to 20 times. Quercetin is a powerful senolytic, meaning it helps the body identify and eliminate senescent or “zombie” cells that accumulate with age and cause inflammation. It also acts as a zinc ionophore and supports respiratory and immune health.

Panax Ginseng has been used for centuries to boost vitality. Our extract is standardized to 7% Ginsenosides, the active compounds responsible for its benefits. It improves cognitive function, including memory and reaction time, and acts as an energizer that combats physical and mental exhaustion.

Calcium Alpha-Ketoglutarate (AKG) is a master regulator of metabolism. It helps stimulate protein synthesis and inhibits protein degradation in muscles. In the context of collagen, AKG is a necessary cofactor for the enzymes that stabilize the collagen helix. Studies suggest AKG can support a younger biological age by influencing cellular energy pathways and reducing frailty.

NIAGEN™ is a patented form of Nicotinamide Riboside (NR), a rigorously tested precursor to NAD+. It efficiently raises NAD+ levels, which are critical for mitochondrial function and cellular repair. By replenishing this vital coenzyme, NIAGEN™ supports healthy aging, boosts daily energy, and improves metabolic stress resistance.

Our Green Tea Extract is standardized for high levels of Epigallocatechin Gallate (EGCG). Beyond its famous antioxidant and metabolism-boosting properties, EGCG inhibits the CD38 enzyme. Since CD38 destroys NAD+, inhibiting it works synergistically with NAD+ precursors to ensure higher, sustained levels of cellular energy.

We use Methylcobalamin, the bioactive form of B12 that the body can use immediately. It is critical for keeping nerves healthy and preventing neurological aging. B12 also supports the production of red blood cells to transport oxygen, ensuring you feel energized and mentally sharp throughout the day.

Betaine acts as a methyl donor, a critical process for DNA regulation and protein function. It is essential for converting homocysteine—a compound that can be harmful in high amounts—back into methionine, thereby supporting heart and blood vessel health. Additionally, Betaine supports liver detoxification processes and helps maintain proper hydration balance within cells.

Betaine is a naturally occurring osmolyte derived from sugar beet. It helps regulate the skin’s water balance, protects proteins from environmental stressors, and reinforces essential structures that keep the barrier strong. This results in improved hydration, reduced irritation, and greater long-term skin comfort.

Calcium Alpha-Ketoglutarate (AKG) is a master regulator of metabolism. It helps stimulate protein synthesis and inhibits protein degradation in muscles. In the context of collagen, AKG is a necessary cofactor for the enzymes that stabilize the collagen helix. Studies suggest AKG can support a younger biological age by influencing cellular energy pathways and reducing frailty.

Colgevity™ is our patented proprietary blend of amino acids like Glycine, Proline, and Hydroxyproline, optimized to mimic human collagen. Unlike standard peptides, this molecular blend provides the precise building blocks your cells need. It actively stimulates fibroblasts to boost the body’s own endogenous collagen production. This process supports skin elasticity, joint structure, and connective tissue strength, revitalizing your collagen matrix from the inside out.

Diglycerin is a multi-hydroxyl humectant that binds water more strongly than glycerin, helping to significantly reduce transepidermal water loss (TEWL). It enhances suppleness, smoothness, and moisture retention, supporting a stable, well-hydrated barrier.

This low molecular weight form of hyaluronic acid penetrates deeper than standard Hyaluronic Acid, providing long-lasting hydration in the upper layers of the skin. It helps improve elasticity and reduce the appearance of fine lines by replenishing the skin’s moisture reservoir and supporting a supple, plumped appearance.

CM-Glucan is derived from yeast beta-glucans transformed into a highly bioactive, water-soluble form. It helps soothe redness, supports faster recovery, and improves skin comfort by strengthening the barrier. Its calming action makes the formula suitable even for sensitive or stressed skin.

Niacinamide supports the production of ceramides and essential structural proteins like filaggrin, helping the skin maintain moisture and integrity. It also reduces oxidative stress, minimizes discoloration, and improves the skin’s response to environmental damage. A gold-standard ingredient for strengthened, smoother, more even-toned skin.

Ectoin is a natural extremolyte that stabilizes skin cells and forms protective hydro-complexes that bind water. It reduces inflammation, shields against pollution and blue light, and prevents UV-induced damage to immune cells. Its exceptional water-binding ability helps maintain optimal hydration and strengthens the barrier under daily stress.

Cellaigie™ boosts the skin’s natural cleanup process known as autophagy — removing damaged proteins and supporting healthier cell function. It also helps regulate energy pathways and reduces signs of cellular senescence. The result is smoother, firmer, more luminous skin with improved resilience as it ages.

These plant-derived exosomes help activate the skin’s own regenerative signals, encouraging fibroblasts to increase collagen and elastin production. By improving the communication between skin cells, they support better dermal density, smoother texture, and reduced wrinkle depth. This ingredient targets the structural protein decline that accelerates visible aging.

RejuveNAD™ is derived from nutrient-rich sunflower sprouts and is designed to stimulate the skin’s own NAD⁺ production. It upregulates NAMPT, the key enzyme in the NAD⁺ salvage pathway, helping cells generate more NAD⁺ internally rather than relying on unstable topical NAD⁺. Higher NAD⁺ levels support stronger cellular repair, better mitochondrial function, and visibly healthier, more energized skin.

Vitamin C is non-negotiable for connective tissue. In Mobiliser, it aids in the repair of cartilage and bones. In SkinSpan™, it fights oxidative stress and pigment formation. Critically, it is the co-factor that allows collagen fibers to twist into a strong triple helix structure; without it, repair processes in skin and joints halt.

Riboflavin is necessary for cell growth and function. It aids in the secretion of mucus in the skin, preventing dryness and cracking. It also plays a role in zinc absorption, another key mineral for skin health. By supporting the body’s energy production, it ensures skin cells have the fuel to repair and regenerate efficiently.

Beta Carotene accumulates in the skin, where it offers protection against UV-induced erythema (sunburn). As a provitamin A carotenoid, the body converts it into Vitamin A as needed, which is crucial for skin cell turnover and repair. It is also known to impart a subtle, healthy “golden glow” to the complexion.

Copper is a cofactor for the enzyme lysyl oxidase, which is responsible for cross-linking collagen and elastin fibers. This process gives skin its strength and “snap-back” elasticity. Copper also plays a role in the production of melanin, the pigment that protects skin from UV radiation, and acts as an antioxidant.

Niacin helps the skin retain moisture by boosting the production of ceramides and fatty acids. It protects skin cells from sun damage and oxidative stress. By supporting microcirculation, it also helps deliver essential nutrients to the skin matrix, resulting in a healthier, more radiant complexion.

Biotin is a water-soluble B-vitamin that is essential for the metabolism of fatty acids and amino acids. In the context of beauty, it plays a specific role in the synthesis of keratin, the structural protein that makes up hair, skin, and nails. Adequate intake supports skin health and helps maintain hair strength and texture.

DracoBelle™ Nu activates the AMPK / FOXO longevity pathway, which stimulates the body’s intrinsic collagen repair mechanisms. It has been shown to significantly increase skin moisture, elasticity, and density. By mimicking the effects of caloric restriction on a cellular level, it promotes a more youthful and resilient skin structure.

Hyaluronic Acid can hold up to 1,000 times its weight in water. Taken orally, it migrates to the skin and connective tissues, increasing moisture content within the dermis. This helps “fill out” fine lines from the inside, giving the skin a plumper, smoother appearance while also supporting the fluid in your joints.

Sourced from the Uttwiler Spätlauber apple, known for its long storage life, this ingredient helps maintain the regenerative potential of skin stem cells. By protecting these essential cells, it combats chronological aging, helping the skin to renew itself more efficiently and maintaining a youthful density and texture.

Ceramides are lipids that hold skin cells together, like mortar in a brick wall. Ceramosides™ are wheat-derived lipids that replenish these levels from the inside. Clinical studies show they significantly improve skin hydration, elasticity, and reduce roughness in as little as 15 days, acting as a powerful internal moisturizer.

Derived from algae, Astaxanthin gives salmon their pink color. It is thousands of times more potent than Vitamin C at neutralizing free radicals. It accumulates in the skin layers, acting as an internal sunscreen that protects collagen from being broken down by UV rays and oxidative stress. Regular intake improves skin moisture, texture, and reduces the appearance of fine lines.

Acerola cherries are among nature’s richest sources of Vitamin C. This extract is not just an antioxidant; Vitamin C is biologically required for the enzymes that stabilize and cross-link collagen molecules. Without it, the body cannot form strong collagen structures. This natural source ensures high bioavailability to protect skin against UV damage and support a glowing complexion.

Vitamin B6 (Pyridoxal 5-Phosphate) is the active form needed to create serotonin and dopamine, the “feel-good” chemicals in your brain. It is vital for mood regulation, reducing tiredness, and supporting the immune system. It also plays a key role in homocysteine metabolism, contributing to heart health.

Magnesium is a cofactor in over 300 enzyme systems. We use the Bisglycinate form because it is gentle on the stomach and highly bioavailable. It effectively relaxes muscles, reduces tension, and calms the nervous system. In Sereniser, it aids sleep; in Essentials, it supports daily energy metabolism and bone health.

L-Theanine is famous for its ability to induce relaxation without sedation. It crosses the blood-brain barrier to increase the production of GABA and alpha brain waves, which are associated with a “flow state” and mental calm. It helps quiet a racing mind, making it easier to focus during the day or drift off to sleep at night.

Serezin™ combines the anti-inflammatory properties of Boswellia (Frankincense) with the soothing effects of Ginger. This duo works to comfort the body physically, which is often a barrier to relaxation. By easing physical tension and supporting a healthy inflammatory response, it prepares both mind and body for a state of deep restfulness.

Holy Basil, or Tulsi, is a revered adaptogen in Ayurveda. Holixer™ uses a unique extraction to deliver a high concentration of Ocimum tenuiflorum. It helps lower cortisol levels and regulates the HPA axis—the body’s stress control center. This results in a calmer mind, better resilience to daily pressures, and improved focus during the day.

Safr’Inside™ is an encapsulated saffron extract that preserves the plant’s delicate bioactives, safranal and crocin. It acts on the brain’s serotonin neurotransmitters to naturally elevate mood and reduce feelings of anxiousness. It helps regulate the stress response, making it easier to unwind and promoting a deeper, more restorative night’s sleep without drowsiness.

NMN (Nicotinamide Mononucleotide) is a vital molecule your body uses to produce NAD+, a coenzyme essential for cellular energy and function. As we age, NAD+ levels naturally decline, leading to fatigue and slower repair processes. Longevir™ NMN is designed to boost these levels efficiently, helping to rejuvenate cells from within, enhance physical endurance, and support optimal metabolic health for a longer, healthier life.

Coenzyme Q10 is found in every cell of the body and is crucial for producing energy in the mitochondria. We use Kaneka Ubiquinol®, the active and most absorbable form of CoQ10. It acts as a potent antioxidant, protecting cells from oxidative stress while supporting cardiovascular health and sustaining vitality. It works synergistically with other longevity ingredients to maximize cellular efficiency.

Colgevity™ is our patented proprietary blend of amino acids like Glycine, Proline, and Hydroxyproline, optimized to mimic human collagen. Unlike standard peptides, this molecular blend provides the precise building blocks your cells need. It actively stimulates fibroblasts to boost the body’s own endogenous collagen production. This process supports skin elasticity, joint structure, and connective tissue strength, revitalizing your collagen matrix from the inside out.

Most Omega-3s come from fish, but fish get it from algae. We go straight to the source with life’s® OMEGA. This pure, vegan oil provides the essential fatty acids DHA and EPA without the heavy metal risk of fish oil. It supports cognitive function, maintains healthy vision, and promotes cardiovascular health by managing triglyceride levels.

Vitamin D3 is essential for the absorption of calcium, ensuring strong bones and teeth. Beyond the skeleton, it modulates the immune system, helping to fight off infections. It also plays a role in muscle function and mood stability. Our dosage provides a robust daily amount to prevent deficiency, common in modern indoor lifestyles.

Chromium is essential for the proper action of insulin. It helps the hormone latch onto cells so glucose can enter and be used for energy. Chromium Picolinate is a highly absorbable form that supports stable blood sugar levels, reduces cravings for sweets, and aids in the metabolism of fats and carbohydrates.

Berberine activates AMPK, known as the body’s “metabolic master switch.” It helps move glucose from the blood into the cells where it is used for energy, mimicking the effects of exercise. It is widely used to support healthy blood sugar regulation, improve lipid profiles, and support gut health.

Reducose® is a patented extract of White Mulberry leaf. It inhibits the enzyme that breaks down sugars and starches in the gut. By taking it with a meal, you can significantly lower the post-meal glucose spike and insulin response. This helps maintain stable energy levels, reduces cravings, and supports metabolic flexibility.

Serezin™ combines the anti-inflammatory properties of Boswellia (Frankincense) with the soothing effects of Ginger. This duo works to comfort the body physically, which is often a barrier to relaxation. By easing physical tension and supporting a healthy inflammatory response, it prepares both mind and body for a state of deep restfulness.

Holy Basil, or Tulsi, is a revered adaptogen in Ayurveda. Holixer™ uses a unique extraction to deliver a high concentration of Ocimum tenuiflorum. It helps lower cortisol levels and regulates the HPA axis—the body’s stress control center. This results in a calmer mind, better resilience to daily pressures, and improved focus during the day.

Safr’Inside™ is an encapsulated saffron extract that preserves the plant’s delicate bioactives, safranal and crocin. It acts on the brain’s serotonin neurotransmitters to naturally elevate mood and reduce feelings of anxiousness. It helps regulate the stress response, making it easier to unwind and promoting a deeper, more restorative night’s sleep without drowsiness.

NMN (Nicotinamide Mononucleotide) is a vital molecule your body uses to produce NAD+, a coenzyme essential for cellular energy and function. As we age, NAD+ levels naturally decline, leading to fatigue and slower repair processes. Longevir™ NMN is designed to boost these levels efficiently, helping to rejuvenate cells from within, enhance physical endurance, and support optimal metabolic health for a longer, healthier life.

Chromium is essential for the proper action of insulin. It helps the hormone latch onto cells so glucose can enter and be used for energy. Chromium Picolinate is a highly absorbable form that supports stable blood sugar levels, reduces cravings for sweets, and aids in the metabolism of fats and carbohydrates.

Berberine activates AMPK, known as the body’s “metabolic master switch.” It helps move glucose from the blood into the cells where it is used for energy, mimicking the effects of exercise. It is widely used to support healthy blood sugar regulation, improve lipid profiles, and support gut health.

Reducose® is a patented extract of White Mulberry leaf. It inhibits the enzyme that breaks down sugars and starches in the gut. By taking it with a meal, you can significantly lower the post-meal glucose spike and insulin response. This helps maintain stable energy levels, reduces cravings, and supports metabolic flexibility.

Panax Ginseng has been used for centuries to boost vitality. Our extract is standardized to 7% Ginsenosides, the active compounds responsible for its benefits. It improves cognitive function, including memory and reaction time, and acts as an energizer that combats physical and mental exhaustion.

We use Methylcobalamin, the bioactive form of B12 that the body can use immediately. It is critical for keeping nerves healthy and preventing neurological aging. B12 also supports the production of red blood cells to transport oxygen, ensuring you feel energized and mentally sharp throughout the day.

Vitamin B6 (Pyridoxal 5-Phosphate) is the active form needed to create serotonin and dopamine, the “feel-good” chemicals in your brain. It is vital for mood regulation, reducing tiredness, and supporting the immune system. It also plays a key role in homocysteine metabolism, contributing to heart health.

Included within our Nordbiotic™ blend, Bifidobacterium breve is a friendly bacteria naturally found in the intestines. It plays a significant role in digesting carbohydrates and fiber. Research suggests this strain supports metabolic health and may help reduce visceral fat. It also exerts anti-inflammatory effects that can positively influence skin clarity and hydration.

Our gut microbiome influences everything from digestion to mood. Nordbiotic™ delivers a high dose of diverse, beneficial bacteria strains that survive the journey to the gut. These probiotics colonize the digestive tract to improve nutrient absorption, strengthen the gut barrier, and communicate with the brain to support mental well-being and immune defense.

Colgevity™ is our patented proprietary blend of amino acids like Glycine, Proline, and Hydroxyproline, optimized to mimic human collagen. Unlike standard peptides, this molecular blend provides the precise building blocks your cells need. It actively stimulates fibroblasts to boost the body’s own endogenous collagen production. This process supports skin elasticity, joint structure, and connective tissue strength, revitalizing your collagen matrix from the inside out.

Vitamin C is non-negotiable for connective tissue. In Mobiliser, it aids in the repair of cartilage and bones. In SkinSpan™, it fights oxidative stress and pigment formation. Critically, it is the co-factor that allows collagen fibers to twist into a strong triple helix structure; without it, repair processes in skin and joints halt.

Unlike standard collagen, UC-II® is biologically active. It works via a mechanism called “oral tolerance” in the gut, which signals the immune system to stop attacking joint cartilage and instead initiate repair. Clinical studies show it is significantly more effective than glucosamine and chondroitin for improving joint comfort and range of motion.

This extract helps improve circulation by strengthening blood vessel walls and supporting nitric oxide production. Better blood flow means better nutrient delivery to joints and muscles. It also possesses strong anti-inflammatory properties that work in tandem with curcumin to reduce pain and improve mobility.

Curcumin is a powerful anti-inflammatory, but it is poorly absorbed. HydroCurc® uses a dispersion technology to deliver high loads of curcuminoids that the body can actually use. It targets inflammation at the source, helping to relieve joint stiffness, support cartilage health, and aid recovery from physical activity.